Large Freeze Dryer
(a)10 series
Lab Scales Desktop(Freeze-dried material 1.5-2KG)
(b)12 series
Lab Scales Vertical(Freeze-dried material 2KG)
(c)18 series
Scientific Research Scales(Freeze-dried material 3KG)
2.Pilot Freeze Dryer:
0.2m²/0.3m²/0.5m²/1m²/2m²/---Pilot Scales(Freeze-dried material 3KG-20KG)
3.Industrial Freeze Dryer:
5㎡/10㎡/20㎡/30㎡/50㎡/100㎡/200㎡/300㎡(Freeze-dried Weight 5T~60T)
4.Customization: set up the specifications you need
(a)Freeze-dried Area
(b)Freeze-dried Weight
(c)Freeze-dried Material
(d)Interlayer Quantity/Size
(e)Cold Trap Temperature
Description
Technical Parameters
As an efficient,stable,and environmentally friendly drying equipment, large freeze dryer have broad application prospects in fields such as biomedicine,food processing,and chemical industry.Large freeze-drying machines still have enormous potential in research and innovation.
Meanwhile,with the development of technologies such as the Internet of Things and big data,large-scale freeze-drying machines will gradually achieve functions such as remote monitoring,fault diagnosis,and automatic maintenance,further improving the reliability and usability of the equipment.In terms of application fields,large-scale freeze-drying machines are expected to further expand their application scope.In addition to traditional fields such as biomedicine,food processing,and chemical engineering,large-scale freeze-drying machines can also be applied in emerging industries such as new materials and new energy,providing strong technical support for the development of these fields.
We provide Large freeze dryer, please refer to the following website for detailed specifications and product information.
Product: https://www.achievechem.com/chemical-equipment/large-freeze-dryer.html
Product Models


parameters table
| Industrial Freeze Dryer | ||||||||||
| Model | ![]() |
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| Types | TF-FZG-5 | TF-FZG-10 | TF-FZG-20 | TF-FZG-30 | TF-FZG-50 | TF-FZG-100 | TF-FZG-150 | TF-FZG-200 | TF-FZG-300 | |
| Freeze-dried Area | m² | 5 | 10.5 | 20 | 30.1 | 50.31 | 98.68 | 148 | 197.4 | 296 |
| Partition Size (L*W*H) |
cm | 100*100*2 | 150*100*2 | 200*100*1.5 | 214*54*1.8 | 310*54*1.8 | 608*54*1.8 | 912*54*1.8 | 1216*54*1.8 | 912*54*1.8 |
| Number of Partition | PCS | 5+1 | 7+1 | 10+1 | (13+1)*2 | (15+1)*2 | (15+1)*2 | (15+1)*2 | (15+1)*2 | (15+1)*2*2 |
| Partition Spacing | mm | 65 | 65 | 70 | 77 | 77 | 77 | 77 | 77 | 77 |
| Number of cart (SUS304) |
PCS | / | / | / | 1 | 2 | 4 | 6 | 8 | 12 |
| Water Catch | KG | 100 | 200 | 400 | 600 | 800 | 1500 | 2000 | 3000 | 4500 |
| Partition Temperature Range | °C | -45 ~ +80 | ||||||||
| Cold Trap Temperature(Min) | °C | ≤-65 | ||||||||
| Ultimate Vacuum Degree | Pa | ≤2.7 | ||||||||
| Electrical Heating(option) | KW | 9 | 16 | 24 | 12*3 | 16*3 | 24*4 | 48*3 | 32*6 | 48*6 |
| Total Power | KW | 40 | 63 | 90 | 125 | 150 | 290 | 380 | 570 | 750 |
| Dimension of unit(approx.) (L*W*H) |
M | 4.5*2.1*3.6 | 6.3*2.1*3.6 | 7.6*2.1*3.6 | 7*2.5*3.6 | 9.1*2.5*3.6 | 15.7*2.5*3.6 | 25*2.5*3.6 | 29*2.5*3.6 | 50*2.5*3.6 |
| Weight | T | 5 | 6.5 | 7.5 | 10 | 13.5 | 20 | 30 | 36 | 60 |
| Electronic control system | ORMON PLC+Industrial Personal Computer-IPC(Remote control with WiFi) | |||||||||
characteristics
Large capacity
Large freeze dryers are engineered to optimize industrial and laboratory workflows by combining high-capacity processing with space-efficient design. These systems can lyophilize substantial volumes of materials-such as pharmaceuticals, biological samples, food products, or soil specimens-in a single batch, significantly boosting production efficiency and reducing processing time. Their ability to handle bulk quantities makes them indispensable for large-scale manufacturing, clinical research, or environmental studies requiring rapid, reliable preservation.
Despite their robust capabilities, these machines are designed with compactness and usability in mind. Their modular, streamlined structures minimize floor space requirements, allowing seamless integration into factories, labs, or cleanrooms without disrupting existing layouts. Key features include user-friendly interfaces, automated controls, and plug-and-play installation, enabling quick setup and operation even in constrained environments. Additionally, their energy-efficient systems and low-maintenance designs lower operational costs while ensuring consistent performance.
By merging high throughput with practical design, large freeze-drying machines empower industries and research institutions to scale operations efficiently, maintain product quality, and adapt to evolving demands in fields ranging from biotechnology to food science. This balance of power and practicality underscores their role as cornerstone equipment in modern production and research facilities.
High efficiency
A large freeze-drying machine excels in preserving the integrity and efficacy of materials by employing sublimation technology, which removes moisture at ultra-low temperatures under vacuum conditions. This process ensures that the original structure, texture, and active ingredients (e.g., enzymes, vitamins, or bioactive compounds) remain intact, unlike traditional drying methods that may cause degradation or shrinkage. The result is a high-quality dried product with extended shelf life, as the absence of water inhibits microbial growth and chemical reactions.
Operationally, these machines are designed for user-friendly efficiency. Equipped with advanced automation systems, they allow precise control over temperature, pressure, and drying time, ensuring consistent quality across batches. Features like touchscreen interfaces, pre-set programs, and real-time monitoring simplify workflows, reducing the need for specialized training. Additionally, their closed-loop systems minimize contamination risks, while data logging capabilities enable traceability and quality assurance.
By combining gentle preservation with operational simplicity, large freeze-drying machines are indispensable in pharmaceuticals, food science, biotechnology, and environmental research, where product stability, batch uniformity, and ease of use are paramount. This dual focus on quality and efficiency makes them a cornerstone of modern manufacturing and laboratory processes.



Key points of operation
Product pre-treatment
The product to be freeze-dried is subjected to appropriate pre-treatment,such as cleaning,cutting,or packaging,to ensure that the product can be freeze-dried uniformly and effectively.
Start up and monitoring
After starting the freeze-drying machine,closely monitor the operation status of the equipment and the freeze-drying process of the product.Pay attention to observing changes in parameters such as temperature and pressure to ensure they remain within the set range.
End and removal
After the freeze-drying process is completed,turn off the equipment according to the operating procedures and wait for a period of time to cool the product to room temperature.Then,carefully remove the freeze-dried product to avoid damage.
Effect on soil
Freeze-dried soil, or lyophilized soil, is a preserved sample created by removing moisture through sublimation-freezing the soil and then applying a vacuum to convert ice directly into vapor without passing through a liquid phase. This process effectively halts biological, chemical, and enzymatic activities, locking in the soil's original composition for long-term analysis. Widely used in environmental science, agriculture, and microbiology, freeze-drying stabilizes nutrients (e.g., nitrogen, phosphorus), microbial communities (bacteria, fungi), and contaminants (heavy metals, pesticides) while preventing degradation. Its primary advantage lies in maintaining sample integrity over extended periods, enabling researchers to store soil for years at room temperature without loss of key properties. This method is invaluable for cross-temporal or cross-regional studies, as it minimizes variability caused by microbial metabolism or moisture-induced chemical changes. Freeze-dried soil is also highly portable, making it ideal for remote fieldwork or large-scale sampling campaigns. In laboratories, it supports reproducible analyses, from DNA/RNA sequencing of soil microbiomes to nutrient cycling experiments. Additionally, it aids in agricultural research by preserving baseline soil conditions for fertilizer trials or land restoration projects. By transforming soil into a durable, lightweight archive, freeze-drying bridges immediate field observations with future scientific inquiry, enhancing our ability to monitor soil health, biodiversity, and environmental impacts over time.
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Due to the special treatment process of the equipment,the soil fertility and crop growth conditions may be affected in some ways.However,in general,dry soil can still grow a variety of crops as long as it is properly treated and restored.Here are some crop types that are suitable for growing in dry soil,including freeze-dried soil:
Drought tolerant crops
Grassland plants:such as cauliflower,daylily,etc.,these crops are drought and cold tolerant,suitable for growing in dry soil.
Plant oil crops,such as peanuts,sunflower,etc.,which can adapt to the growth of dry conditions and provide rich vegetable oil.
Fruit trees
Apple,pear:These fruit trees have unique advantages in terms of fruit size,color and taste,and have strong adaptability to the growing environment.
Pomegranate,date:Also belong to the more practical value of fruit trees,can grow well in dry soil.
Other crops
Some vegetables:such as pumpkin,zucchini,etc.,these vegetables have relatively low soil requirements and can grow in a drier environment.
Some herbs:such as lavender,rosemary,etc.,these plants have a strong drought tolerance,suitable for planting in dry soil.
It is important to note that while these crops are suitable for growing in dry soil,it does not mean that they can be grown directly on untreated freeze-dried soil.Before planting,the soil needs to be properly treated and restored to ensure its fertility and crop growing conditions are at their best.
In addition,the freeze-drying process may change some physical and chemical properties of the soil,such as soil structure,moisture content,nutrient distribution,and so on.Therefore,before planting,it is recommended to conduct detailed testing and analysis of the soil to understand the specific situation of its fertility and crop growing conditions.Based on the test results,the corresponding soil improvement and fertilization plan can be formulated to improve the yield and quality of crops.
Key Impacts of Freeze-Drying on Soil
Soil Structure
Freeze-drying may cause collapse of pore spaces or aggregation disruption, affecting water retention, aeration, and root penetration. Rehydrated soil might initially exhibit reduced porosity compared to fresh samples.
Moisture Content
The process eliminates all free and bound water, requiring careful rehydration protocols to restore field-like moisture levels. Over- or under-watering during restoration can skew nutrient availability or microbial activity.
Nutrient Distribution & Bioavailability
Soluble nutrients (e.g., nitrates, phosphates) may concentrate during drying or redistribute unevenly upon rehydration. Additionally, microbial dormancy induced by desiccation could temporarily reduce nutrient cycling until populations recover.
pH and Chemical Equilibria
Shifts in ionic concentrations or mineral solubility during freeze-drying might slightly alter soil pH, impacting nutrient uptake by crops.
Recommendations for Post-Freeze-Drying Soil Management
Comprehensive Soil Testing
- Conduct nutrient profiling (N-P-K, micronutrients), pH analysis, and texture assessments to establish a baseline for improvement.
- Evaluate microbial biomass and diversity via DNA/RNA sequencing to gauge soil health.
01
Soil Amendment Strategies
- Organic Matter Addition: Incorporate compost, manure, or biochar to restore structure, porosity, and water-holding capacity.
- pH Adjustment: Apply lime (if acidic) or sulfur (if alkaline) to optimize nutrient availability.
- Nutrient Balancing: Supplement with targeted fertilizers based on deficiency patterns (e.g., potassium for drought resilience).
02
Microbial Reactivation
- Introduce beneficial microbes (e.g., mycorrhizal fungi, nitrogen-fixing bacteria) to accelerate nutrient cycling and root colonization.
03
Controlled Rehydration & Conditioning
- Gradually reintroduce water to mimic natural rainfall patterns, avoiding osmotic shock.
- Allow equilibration periods (e.g., 1–2 weeks) before planting to stabilize soil properties.
04
Crop-Specific Adaptation
- Select drought-tolerant or nutrient-efficient varieties if soil structure or fertility remains suboptimal.
- Implement precision agriculture techniques (e.g., sensor-based irrigation) to optimize resource use.
05
While freeze-drying provides a stable, long-term preservation method for soil analysis, its effects on structure, moisture, and nutrient dynamics necessitate tailored rehabilitation strategies. By integrating rigorous testing, targeted amendments, and microbial rejuvenation, farmers and researchers can mitigate process-induced changes, ensuring that rehydrated soil supports high-yield, sustainable agriculture. This proactive approach transforms freeze-dried soil from a preserved archive into a living resource for crop productivity.
Freeze-dried medicinal materials and common medicinal materials
Preparation process
Freeze-dried medicinal materials:vacuum freeze-drying technology is used to freeze fresh medicinal materials at low temperatures,and then the water is sublimed directly from solid to gas through decompression technology,so as to obtain dry medicinal materials.
Common medicine:The water in medicinal materials is usually removed by traditional methods such as drying and drying.
Ingredient retention
Freeze-dried medicinal materials:Because it is dried at low temperature,it can retain the active ingredients and efficacy of medicinal materials to the maximum extent,and avoid the destruction of medicinal materials by high temperature.
Common medicine:Traditional drying methods may cause some components of the medicine to be lost due to high temperature,thus affecting the efficacy.
Efficacy
Freeze-dried medicinal materials:Due to the good retention of active ingredients,the efficacy is usually superior to that of ordinary medicinal materials.
Common medicine:The efficacy may be reduced by the loss of ingredients.
Degree of cleanliness
Freeze-dried medicinal materials:After extraction,the soil is usually washed by hand before it is dried,so the impurity content is less and it is cleaner.
Common medicine:may not be so strict cleaning treatment,impurity content is relatively high.
Storage period
Freeze-dried medicinal materials:Because the moisture content is very low,and to avoid the growth of microorganisms and self-oxidation of medicinal materials,so the preservation period is long,not easy to deteriorate.
Common medicinal materials:the storage period is relatively short,easy to be damp,mildew or deterioration.
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