5L Rotary Evaporator
(1)1L/2L---Manual lifting with irony base/Manual lifting with SS base/Electric lifting
(2)3L/5L/10L/20L/30L/50L---Manual Lifting/Electric Lifting
***Price List for whole above, inquire us to get
2. Customization:
(1)Design support
(2)Directly supply the Senior R&D organic intermediate, shorten your R&D time and cost
(3)Share the advanced purifying technology with you
(4)Supply the high quality chemicals and analysis reagent
(5)We want to assist you on Chemical Engineering (Auto CAD, Aspen plus etc.)
3. Assurance:
(1)CE and ISO certification Registered
(2)Trademark: ACHIEVE CHEM(since 2008)
(3)Replacement parts within 1-year for free
Description
Technical Parameters
5L rotary evaporator, also known as 5l rotovap, is a new type of evaporation equipment mainly used for concentration, crystallization, drying, separation, and solvent recovery in pharmaceutical, chemical, and biopharmaceutical industries. Its working principle is to heat the rotating bottle at a constant temperature under vacuum conditions, causing it to rotate at a constant speed.
The material forms a large area thin film on the bottle wall and evaporates efficiently. The solvent is evaporated and cooled by an efficient glass condenser, which is then recycled and collected into the bottle, greatly improving the evaporation efficiency. It is particularly suitable for the concentration and purification of biological substances that are prone to decomposition and denaturation at high temperatures.
Product Introduction
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The process of forming a large area thin film on the bottle wall of a rotating evaporator is as follows:
● Install a thin film of liquid product on the inner side of the vertical evaporation pipeline, which is generated by a rotating wiper system. ● The rotating wiper can evenly distribute the feed liquid flowing downwards on the inner side of the pipe wall. ● Based on the liquid viscosity, type of wiper system, rotational speed, and liquid flow rate, the thickness of the film is approximately 0.1-0.5 millimeters.
By rotating the bottle wall of the evaporator through the above steps, a large area of thin film can be formed. |
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Product Differentiation
A 5L rotary evaporator belongs to the small equivalent size category in rotary evaporators. Rotating evaporators are usually divided into small, medium, and large ones, with corresponding capacities and sizes as follows:
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Small rotary evaporator: he capacity is usually below 10L, suitable for laboratory scale operations such as organic synthesis, chemical analysis, sample processing, etc. |
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Medium rotary evaporator: The capacity is usually between 10L and 50L, suitable for medium scale operations, such as pilot production, process research, industrial testing, etc. |
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Large rotary evaporator: The capacity is usually above 50L, suitable for large-scale production operations, such as industrial production in industries such as pharmaceuticals, chemicals, and food. |
Applications
5L Rotary evaporator is a commonly used laboratory equipment mainly used for operations such as evaporation, concentration, separation, and purification. It has a wide range of applications, including but not limited to the following:
▲ Chemical industry: Rotating evaporators have a wide range of applications in the chemical industry, including dehydration, deacidification, concentration, purification, and separation. They can also be used for the separation of plant extracts and the concentration of biochemical drugs.
▲ Pharmaceutical field:Rotating evaporators also have important applications in the pharmaceutical field, which can be used for the preparation of natural plant extracts, traditional Chinese medicine, catalysts, anticancer drugs, metal organic compounds, and other products.
▲ Food field: Rotating evaporators can be used for food processing and the concentration and separation of extracted materials, such as juice, tea, spices, etc.
▲ Environmental protection: Rotating evaporators can be used for waste liquid treatment and recovery, such as wastewater treatment and heavy metal recovery.
▲ Other fields: Rotating evaporators can also be used in fields such as crystallization, drying, separation, and solvent recovery, as well as various applications in other laboratories and industrial production.
Main components, their materials, and applicable categories
Shell
Material: Stainless steel
Application category: Stainless steel shell with corrosion resistance, high temperature resistance, durable and other characteristics, suitable for a variety of laboratory environments, especially need to withstand a certain pressure and temperature change occasions.
Internal parts
Heater
Material: Ceramic or stainless steel
Applicable category: Ceramic heater has excellent high temperature resistance, suitable for high temperature heating experiments; Stainless steel heaters have better corrosion resistance and mechanical strength, suitable for a variety of experimental environments.
Rotor
Material: Stainless steel
Application Category: Stainless steel rotor corrosion resistance, high strength, suitable for experimental environments that need to withstand rotation and friction, such as sample stirring and mixing during rotary evaporation.
Thermostatic bath
Material: High quality plastic or stainless steel
Application category: High quality plastic thermostatic tank has good thermal stability and chemical stability, suitable for experiments requiring precise temperature control; Stainless steel thermostatic tank has higher corrosion resistance and mechanical strength, suitable for harsher experimental environments.
Glass pieces
Material: high borosilicate glass
Application category: High borosilicate glass has the characteristics of high light transmittance, high temperature resistance, good chemical stability, etc., suitable for observation experiment process and experimental environment under high temperature heating. The glass parts of the evaporating bottle and condensing tube of the rotary evaporator are usually made of this material.
Sealing parts
Material: polytetrafluoroethylene (PTFE) and rubber composite seal
Application category: PTFE and rubber composite seals can maintain high vacuum, suitable for experiments requiring high vacuum environment. They have good corrosion resistance and sealing properties, which can ensure that there will be no leakage problems during the long use of the rotary evaporator.
Other components
Bracket
Material: Aluminum alloy or stainless steel
Applicable category: Aluminum alloy bracket lightweight and corrosion resistant, suitable for general laboratory environment; The stainless steel bracket has higher strength and corrosion resistance, which is suitable for harsher experimental environments.
Condenser
Material: high borosilicate glass or stainless steel
Application category: Condensers are usually made of materials similar to glass parts to ensure good thermal conductivity and chemical stability. High borosilicate glass condenser is suitable for high temperature and corrosive environment; Stainless steel condensers have higher strength and corrosion resistance.
Daily cleaning operation specification
Preparations before cleaning
Safety protection
Wear chemical protective gloves (made of organic solvent-resistant materials), goggles and a lab coat to prevent solvent splashing or skin contact.
Ensure good ventilation in the operation area. It is recommended to clean in a fume hood to avoid the accumulation of volatile solvents.
Turn off the power of the equipment and unplug the power cord to prevent accidental start-up or electrical short circuit.
Tool and material preparation
Cleaning solvent: Select based on the nature of the residual solvent (such as ethanol, acetone, deionized water, dilute acid/alkali solution).
Cleaning tools: Soft brush, anti-static soft cloth, silicone spatula, waste liquid collection bottle, ultrasonic cleaner (optional).
Consumables: Vacuum grease, sealing ring (spare), filter paper, nitrogen gun (for drying).
Cleaning Steps and Key Points of Operation
Preliminary rinse:
Immediately after the experiment, rinse the inner wall of the evaporation flask with an appropriate amount of ethanol (50-100 ml), rotate the evaporation flask (50-80 RPM) to ensure uniform coverage of the solvent, and continue for 2-3 minutes. Then, pour out the waste liquid.
If the residue is a high-viscosity or high-boiling-point solvent (such as DMSO, resin type), it can be rinsed with acetone first and then washed a second time with ethanol.
Deep cleaning
Disassemble the evaporation flask and rinse the inner wall with deionized water to remove water-soluble impurities.
If the residue is inorganic salts or metal ions, soak in 1% dilute hydrochloric acid for 10 minutes, then rinse with deionized water until neutral.
Stubborn stains (such as tar) can be gently scraped off with a soft silicone spatula to avoid scratching the glass.
External cleaning
Use an anti-static soft cloth dipped in ethanol to wipe the outer shell of the condenser to remove surface oil stains or solvent residues.
Internal flushing
Inject ethanol (50mL) through the vacuum interface of the condenser, slowly rotate the evaporation bottle to make the ethanol circulate and flush the internal pipes, and then discharge it to the waste liquid bottle.
If there are algae or biofilms inside the condenser, circulate and rinse with a 0.5% sodium hydroxide solution for 15 minutes, and then rinse with deionized water until the pH=7.
Fin maintenance
Disassemble the condenser end cover every week and use a soft brush to remove the dust between the fins to prevent blockage and affect heat dissipation.
When the fouling is severe, use compressed air (pressure ≤0.3MPa) to blow in the opposite direction to prevent the fins from deforming.
Sealing ring maintenance
Remove the sealing ring, and wipe the surface oil stains and solvent crystals with a soft cloth dipped in ethanol. Avoid using hard objects to scrape.
Check whether the sealing ring is aged or cracked. If there is a problem, replace it immediately.
After cleaning, apply a thin layer of vacuum grease (thickness ≤0.1mm). When reinstalling, ensure that the sealing ring is not twisted.
Interface cleaning
Use filter paper dipped in ethanol to wipe the glass interface to remove residual vacuum grease or dirt.
Sandpaper or metal tools must not be used to polish the interface to prevent scratches and air leakage.
Pump oil replacement
Turn off the power of the vacuum pump, drain the waste oil to the waste liquid bucket, and inject new oil to 1/2-2/3 of the oil window.
If the pump oil is emulsified or its color darkens, it needs to be replaced immediately. After distilling high-viscosity solvents, it is recommended to shorten the oil change cycle to 50 hours.
Pipeline cleaning
Disassemble the vacuum pipeline, rinse the interior with ethanol to remove the solvent residue.
Dry the pipeline with a nitrogen gun to prevent water vapor from corroding or breeding microorganisms.
Daily maintenance:
After each experiment, drain the bath solution and wipe the inner wall of the bath tank with a soft cloth to remove salt scale or oxide layer.
After distilling the salt-containing solvent, soak it in 5% dilute hydrochloric acid for 30 minutes, and then rinse it three times with deionized water.
Long-term storage
If the equipment is not used for a long time, drain the bath liquid and clean it thoroughly to prevent the crystallization of the bath liquid from damaging the heating tube.
Cleaning Precautions
Solvent Selection and Safety
It is strictly prohibited to clean fluorine-containing rubber sealing rings with chlorinated solvents (such as dichloromethane), as it may cause swelling and failure.
Avoid direct contact of strong acids and alkalis with glass components. Dilute before use (such as 1% dilute hydrochloric acid or 0.5% sodium hydroxide).
When cleaning flammable solvent residues, keep away from open flames and high-temperature equipment. Do not use metal tools to strike.
Component protection
Handle the glass components with care. Use a dedicated bracket to move the evaporation flask to avoid stress cracking caused by one-handed grasping.
The sealing ring should be stored in a cool and dry place, avoiding direct sunlight or high-temperature environments that may cause rubber aging.
Electrostatic protection
During the cleaning process, use anti-static soft cloths to prevent the explosion of flammable gases caused by static electricity.
When performing ultrasonic cleaning, ensure that the cleaning instrument is well grounded to prevent the accumulation of static electricity.
Inspection and record-keeping after cleanin
Functional test
After reassembling the equipment, turn on the vacuum pump to check the sealing performance (vacuum degree ≤-0.095MPa).
Inject a small amount of water to test whether the heating bath heats up normally and whether the condenser leaks.
Record Management
Record the cleaning date, the cleaning area, the solvents used and consumables (such as the replacement of sealing rings).
If any component damage or performance decline is found, report for repair in a timely manner and record the repair content.
Common Problems and Solutions
Residual crystals on the inner wall of the evaporation flask
Reason: The solvent evaporated too quickly or was not rinsed in time.
Solution: Dissolve it ultrasonically with a small amount of ethanol or gently scrape it off with a soft silica gel spatula (avoid scratching the glass).
There is scale at the outlet of the condenser
Reason: The hardness of the cooling water is high or it has not been cleaned for a long time.
Solution: Circulate and clean with a 5% citric acid solution for 1 hour, then rinse with deionized water until pH=7.
The sealing ring is leaking air
Reason: Aging of the sealing ring, improper installation or impurities on the surface.
Solution: Replace the sealing ring with a new one, apply vacuum grease and reinstall it to ensure there are no particles at the interface.
The pumping efficiency of the vacuum pump has decreased
Reasons: Emulsification of pump oil, oil contamination or pipeline blockage.
Solution: Replace the vacuum pump oil, clean the air inlet filter screen, and blow the pipeline back with nitrogen
Summary
Daily cleaning is the key to ensuring the performance and safety of the 5L rotary evaporator. Through timely and standardized operation, the service life of the equipment can be effectively prolonged, cross-contamination can be avoided, and experimental risks can be reduced. It is suggested that the laboratory formulate standardized cleaning procedures and regularly train the operators to ensure the quality and efficiency of cleaning.
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