Single Rotary Tablet Press

Single Rotary Tablet Press is a kind of mechanical equipment used in pharmaceutical,chemical and other industries to press powder or granular materials into regular shaped tablets by single axis rotation.

Single Rotary Compression Machine in the chemical industry application case fully demonstrates its advantages in improving production efficiency, efficiency,guaranteeing product quality and reducing production costs.Through the introduction of this machine,enterprises can realize faster,more stable and more economical production of solid pharmaceuticals.With the continuous development of the chemical industry,the application prospect of it will be more broad.

It is widely used and important in the chemical industry.The following is a segmented presentation of a case study of its application in the chemical industry:

Background
A large chemical company needs to manufacture large quantities of solid pharmaceuticals of different specifications during the process.In order to improve efficiency and product quality,the enterprise introduced the advanced it.

application
Improvement:Through the high-speed operation of it,the enterprise can significantly shorten the  cycle and improve it.Compared with the traditional multi-rotary tablet press,it has higher stability and lower failure rate.
Guarantee product quality:The machine adopts advanced touch screen and PLC control system,which can accurately control various parameters in the tablet pressing process.
Strong adaptability:the single rotary tablet press can adapt to the needs of solid pharmaceuticals with different specifications and formulations.By replacing the molds and adjusting the parameters,the enterprise can easily realize the diversified production of products.

Case effect
Since the introduction of it,the chemical enterprise's efficiency has been significantly improved and product quality has been effectively guaranteed.At the same time,the application of this equipment also reduces the cost and labor input,bringing considerable economic benefits to the enterprise.

Summary
Single Rotary Compression Machine in the chemical industry application case fully demonstrates its advantages in improving,ensuring product quality and reducing costs.With the continuous development of the chemical industry,the application prospects will be more broad.

The way of controls pressure and time during the tabletting depends largely on the type and configuration of the tablet press.

Pressure Control
Manual powder tablet presses are usually equipped with a device,such as a knob or handle.
The operator first determines the required range based on the characteristics and requirements of the desired material.
It is then gradually adjusted by rotating or moving the button,handle or adjusting screw on it adjusting device until the desired it value is reached.
During the process,it may be necessary to test it several times to ensure that it set is appropriate,check the results of the press and make fine adjustments as needed.
Automatic Adjustment:
Some high-end tablet presses are equipped with automatic control systems that automatically adjust based on preset parameters.
These systems often incorporate sensors and computer algorithms that monitor changes in real time during the tabletting and automatically adjust regulator to maintain a constant output.
Accuracy and Stability:
Whether manually or automatically controlled,the accuracy and stability of regulation is critical to obtaining high quality tabletting results.
Accurate control ensures consistency in key parameters such as tablet thickness,weight and hardness.

Time Control
For manual tablet presses,the tablet pressing time is determined primarily by the operator based on experience and experimentation.
The operator needs to control the tablet pressing time by adjusting the operating speed or the pressing cycle of the tablet press according to the nature of the herbs,their thickness and the performance of it.
This method is simple and direct,but may be affected by human factors and requires the operator to have certain experience and skills.
Automatic Control System:
Some high-end tablet presses are equipped with automatic control systems that can automatically control the tablet pressing time based on the nature of the herbs,parameters and conditions.
These systems are able to monitor in real time the various parameters of the tabletting,such as herb flow,mold temperature,etc.,and automatically adjust the tabletting time accordingly to achieve optimal results.
Specialized control systems:
For herbs or chemical raw materials that require high precision,specialized control systems can be used to control the tabletting time.
These systems usually combine high-precision sensors and advanced control algorithms to ensure precise control of tabletting time,thus improving product quality.

Summary
During the tabletting,controls it through manual or automatic control systems.Accurate it control is critical to obtaining high quality tabletting results.Operators need to select the right control method for the situation and make appropriate adjustments and optimizations as needed.

The Single Station Tablet Punching Machine has a wide range of applications in the pharmaceutical industry.Below is a specific application case study,illustrated with information from the referenced article:

Application Case:Production of Anti-PD-1 Monoclonal Antibody Drug Treprostinil Injection for Junshi Biotech
1.Background
Drug Information:Teraplizumab Injection (Topic®) is an anti-PD-1 monoclonal antibody drug independently developed by Junshi Biologicals.
Indications:The drug is mainly used for the perioperative treatment of adult patients with resectable stage IIIA-IIIB non-small cell lung cancer (NSCLC).
2.Role
Tablet Punching Process:It is used to press tablets during the manufacture of Trepolizumab Injection,which may be an auxiliary device for a certain part of the manufacturing,such as the preparation of certain auxiliary agents or raw materials.
Advantage:It is characterized by high efficiency,which can ensure the consistency of the quality of the tablets,thus indirectly guaranteeing the overall quality of Teraplizumab Injection.
3.Specific application details
Equipment selection:JUNSHI BIOLOGICAL selected it which is suitable for its production line according to its production requirements and drug characteristics.
Operation Procedure:The operator sets the parameters of the tableting machine,such as pressure,time,etc.,according to the drug formula and process,and then puts the raw materials into the tableting machine to press the tablets.
Quality control:During the tablet pressing ,Junshi Bio strictly follows the requirements of GMP (Good Manufacturing Practice),and strictly manages and controls the operation,maintenance and cleaning of the tablet press to ensure that the quality of the tablets meets the standards.
4.Achievements and Impact
New Drug Listing:The listing application for the new indication of Trepolizumab Injection was approved by the National Drug Administration (NMPA) on January 2,2024,making it the first perioperative therapy for lung cancer approved in China and the second in the world.
Industry significance:This achievement not only reflects Junshi Bio's R&D strength in the field of biopharmaceuticals,but also demonstrates the important role of it in the pharmaceutical industry.Through this case,we can see that it plays an irreplaceable role in guaranteeing drug quality and improving efficiency.
5.Subsequent Development
Technology Upgrade:With the continuous development of the pharmaceutical industry,Junshi Bio may continue to introduce more advanced it to meet its growing needs.
Market Expansion:With the successful launch of Teraplizumab Injection,Junshi Bio may further expand its product line and apply Single Station Tablet Punching Machine in the production of more drugs.

Market share distribution

Due to the fierce market competition,the market share distribution of single rotary tablet press is relatively dispersed.The performance of different manufacturers in the market is quite different,and the market share is also different.Some leading enterprises have high visibility and influence in the market, occupying a large market share; However,some small and medium-sized enterprises have gained a certain market share through differentiated competition and market segmentation positioning.

Market Trends

With the rapid development of the pharmaceutical industry and the continuous improvement of people's health needs,the demand for single rotary tablet press will continue to grow.At the same time,with the continuous progress of technology and the intensification of market competition,manufacturers will continue to strengthen technological innovation and quality control,improve product performance and competitiveness.This will drive the market to become more efficient,smarter and greener.

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